SLI research, including the brain donation program, is conducted at the Boston University CTE Center and the SLI-BU CTE Brain Bank.
SLI and BU CSTE Studies
Brain Donation Registry: Current and former athletes and military personnel may donate their brain or spinal cord to the BU CTE Center after death. For more information on the brain donation registry, please contact Patrick Kiernan at email@example.com or (617) 414-1187.
LEGEND (Longitudinal Examination to Gather Evidence of Neurodegenerative Disease): Participants in the LEGEND study take part in yearly telephone interviews as well as yearly online questionnaires. They may also provide a saliva sample for genetic testing. Both those with and without a history of concussions can participate in the LEGEND study. If you are interested in participating in LEGEND, please contact Kaitlyn Perry at firstname.lastname@example.org or (617) 414-8389.
DETECT (Diagnosis and Evaluation of Traumatic Encephalopathy with Clinical Tests): This study is the first research project on CTE to be funded by the National Institutes of Health (NIH), with support from the National Institute of Neurologic Diseases and Stroke (NINDS), the National Institute on Aging (NIA), and the National Institute of Child Health and Human Development (NICHD). The ultimate goal of this study is to develop methods of diagnosing CTE during life through the use of a variety of tests, including MRI scans (such as diffusion tensor imaging), MRS scans (also known as a “virtual biopsy”), blood tests, and measures of proteins in spinal fluid. Participants will also undergo neurological, psychiatric, and cognitive assessments, as well as genetic testing. The study will include 150 former NFL players (ages 40-69) and 50 same-age “control” athletes who played non-contact sports. Recruitment will be starting in November 2011. For more information or if you are interested in participating please contact Nate Frittsat email@example.com or (617) 414-8391.
BU-VA-SLI CTE Brain Bank: Family members of deceased athletes may donate their loved one’s brain and spinal cord after their death to the VA-BU-SLI CTE Brain Bank to be examined neuropathologically for evidence of CTE or other central nervous system disorders. The family member(s) will be interviewed for a history of their loved one, including their loved one’s athletic and concussion history, educational and occupational history, medical history and history of cognitive, behavioral, and mood symptoms. To learn more, please contact Patrick Kiernan at firstname.lastname@example.org or (617) 414-1187.